Chemical Structure : FH535
CAS No.:
108409-83-2
FH535
(FH 535;FH-535)
Catalog No. : PC-44658Not For Human Use, Lab Use Only.
FH535 is a potent, dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment, inhibits the Wnt/β-catenin pathway.
Packing Price Stock Quantity 10 mg $58 In stock 0 1 2 3 4 5 25 mg $98 In stock 0 1 2 3 4 5 50 mg $148 In stock 0 1 2 3 4 5 100 mg $228 In stock 0 1 2 3 4 5 250 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4465801
Biological Activity
FH535 is a potent, dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment, inhibits the Wnt/β-catenin pathway.β-catenin/Tcf –mediated transcription and inhibits the Wnt/β-catenin pathway.
Physicochemical Properties
M.Wt
361.2005
Formula
C13H10Cl2N2O4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Benzenesulfonamide, 2,5-dichloro-N-(2-methyl-4-nitrophenyl)-
References
1. Handeli S, et al. Mol Cancer Ther.
2. Gedaly R, et al. PLoS One
3. Su H, et al. J Transl Med
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