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Chemical Structure : FH535
CAS No.: 108409-83-2
Catalog No.: PC-44658Not For Human Use, Lab Use Only.
FH535 is a potent, dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment, inhibits the Wnt/β-catenin pathway.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $58 | In stock | |
| 25 mg | $98 | In stock | |
| 50 mg | $148 | In stock | |
| 100 mg | $228 | In stock | |
| 250 mg | Get quote |
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FH535 is a potent, dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment, inhibits the Wnt/β-catenin pathway.
FH535 antagonizes β-catenin/Tcf–mediated transcription and inhibits the Wnt/β-catenin pathway.
FH535 shows antiproliferation effect on transformed colon lung and liver cell lines.
| M.Wt | 361.2005 | |
| Formula | C13H10Cl2N2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Benzenesulfonamide, 2,5-dichloro-N-(2-methyl-4-nitrophenyl)- |
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1. Handeli S, et al. Mol Cancer Ther. 2008 Mar;7(3):521-9.
2. Gedaly R, et al. PLoS One. 2014 Jun 18;9(6):e99272.
3. Su H, et al. J Transl Med. 2015 Mar 31;13:104.
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