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Chemical Structure : FLT3 inhibitor 7c
CAS No.: 2088735-51-5
Catalog No.: PC-38742Not For Human Use, Lab Use Only.
FLT3 inhibitor 7c is a novel potent FLT3 inhibitor with IC50 of 207.2, 215.3 and 32.5 nM for FLT3 (WT), FLT3 (D835Y) and FLT3 (ITD), respectively.
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|---|---|---|---|
| 5 mg | $138 | In stock | |
| 10 mg | $218 | In stock | |
| 25 mg | $378 | In stock | |
| 50 mg | $588 | In stock | |
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FLT3 inhibitor 7c is a novel potent FLT3 inhibitor with IC50 of 207.2, 215.3 and 32.5 nM for FLT3 (WT), FLT3 (D835Y) and FLT3 (ITD), respectively.
FLT3 inhibitor 7c inhibits Molm-13 and MV4-11 proliferation with IC50 of 95.5 and 61.9 nM, respectively.
FLT3 inhibitor 7c inhibits FLT3 signaling in FLT3-ITD+ Molm-13 and MV4-11 cells in vitro.
FLT3 inhibitor 7c inhibits FLT3-downstream effector STAT5 phosphorylation and total STAT5 protein in Molm-13 and MV4-11 cells.
| M.Wt | 254.26 | |
| Formula | C15H11FN2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5-(4-Fluorophenyl)-N-phenyl-2-oxazolamine |
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1. Hyo Jeong Kim, et al. Molecules. 2020 Nov 5;25(21):5154.
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