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FN075

Chemical Structure : FN075

CAS No.: 864405-82-3

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FN075 (FN 075)

Catalog No.: PC-62185Not For Human Use, Lab Use Only.

FN075 is a small-molecule inhibitor targeting Escherichia coli amyloid biogenesis and biofilm formation.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    FN075 is a small-molecule inhibitor targeting Escherichia coli amyloid biogenesis and biofilm formation; stimulates α-synuclein amyloid fiber formation.
    FN075 significantly attenuates virulence in a mouse model of urinary tract infection.

    Physicochemical Properties

    M.Wt 481.489
    Formula C26H18F3NO3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (R)-7-(naphthalen-1-ylmethyl)-5-oxo-8-(3-(trifluoromethyl)phenyl)-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3-carboxylic acid

    References

    1. Cegelski L, et al. Nat Chem Biol. 2009 Dec;5(12):913-9.

    2. Clark MA, et al. Nat Chem Biol. 2009 Sep;5(9):647-54.

    3. Nors Perdersen M, et al. Sci Rep. 2015 May 28;5:10422.

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