FORX-864 | RAD52 inhibitor | Probechem Biochemicals

Chemical Structure : FORX-864

FORX-864 (FORX864)

Catalog No.: PC-28497Not For Human Use, Lab Use Only.

FORX-864 is a potent, selective, covalent RAD52 inhibitor with IC50 of 5 nM in FP assays, inhibits RAD52-dependent single-strand annealing with IC50 of 0.96 uM in U2OS SA-GFP SSA reporter assay.

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Biological Activity

FORX-864 is a potent, selective, covalent RAD52 inhibitor with IC50 of 5 nM in FP assays, inhibits RAD52-dependent single-strand annealing with IC50 of 0.96 uM in U2OS SA-GFP SSA reporter assay.

Physicochemical Properties

M.Wt	716.80
Formula	C36H33FN4O7S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-acrylamido-2-fluorobenzyl)-2-(3-(2-((2-(3-(5-carboxy-4-methylthiazol-2-yl)phenoxy)ethyl)(methyl)amino)ethoxy)phenyl)thiazole-5-carboxylic acid

References

1. Bocquet N, et al. J Am Chem Soc. 2026 Oct 8. doi: 10.1021/jacs.6c16278.

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FORX-864 (FORX864)

Biological Activity

Physicochemical Properties

References

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