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Chemical Structure : FOXO1-IN-8
CAS No.: 2678530-68-0
Catalog No.: PC-60015Not For Human Use, Lab Use Only.
FOXO1-IN-8 (FOXO1 inhibitor 8) is a small molecule, selective FOXO1 inhibitor that inhibits FOXO-dependent glucose production devoid of lipogenic activity in hepatocytes.
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FOXO1-IN-8 (FOXO1 inhibitor 8) is a small molecule, selective FOXO1 inhibitor that inhibits FOXO-dependent glucose production devoid of lipogenic activity in hepatocytes.
FOXO1 inhibitor 8 shows beneficial effects of FOXO1 inhibition on diabetic hyperglycemia by reducing hepatic glucose production.
| M.Wt | 243.27 | |
| Formula | C12H13N5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-(2-(methylamino)pyrimidin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one |
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1. Langlet F, et al. Cell. 2017 Nov 2;171(4):824-835.e18.
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