Chemical Structure : FPFT-2216
CAS No.: 2367619-87-0
Catalog No.: PC-20149Not For Human Use, Lab Use Only.
FPFT-2216 (FPFT2216) is a thalidomide derivative cereblon modulator that shows an inhibitory effect toward IKZF1 protein level, upregulates the production of IL-2 and degrades IKZF1 as well as CK-1α among ubiquitin–proteasomal degradative substrates of IMiDs.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $288 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | $758 | In stock | |
| 100 mg | Get quote | ||
| 1 g | Get quote |
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FPFT-2216 (FPFT2216) is a thalidomide derivative cereblon modulator that shows an inhibitory effect toward IKZF1 protein level, upregulates the production of IL-2 and degrades IKZF1 as well as CK-1α among ubiquitin–proteasomal degradative substrates of IMiDs.
| M.Wt | 262.29 | |
| Formula | C11H10N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-[4-(4-Methoxy-3-thienyl)-1H-1,2,3-triazol-1-yl]-2,6-piperidinedione |
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1. Mingxing Teng, et al. J Med Chem. 2022 Jan 13;65(1):747-756.
2. Gemechu Y,et al. Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):11802-11807.

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