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Chemical Structure : FPR2 agonist MR-39
Catalog No.: PC-20787Not For Human Use, Lab Use Only.
FPR2 agonist MR-39 is a ureidopropanamide agonist of formyl peptide receptor-2 (FPR2) with EC50 of 3.9 uM.
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FPR2 agonist MR-39 is a ureidopropanamide agonist of formyl peptide receptor-2 (FPR2) with EC50 of 3.9 uM.
MR-39 reduces IL-1β and TNF-α levels in LPS-stimulated microglial cells.
MR-39 elicits FPR2-mediated anti-inflammatory effects in rat microglia and also displays suitable pharmacokinetic characteristics.
| M.Wt | 508.95 | |
| Formula | C27H23ClF2N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ewa Trojan, et al. Cells. 2021 Jun 17;10(6):1524.
2. Stama M.L., et al. Eur. J. Med. Chem. 2017;141:703–720.
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