FPR2 agonist compound 8

Chemical Structure : FPR2 agonist compound 8

Catalog No.: PC-24177Not For Human Use, Lab Use Only.

FPR2 agonist compound 8 is a potent, selective agonist of formyl peptide receptor 2 (FPR2/ALX, Lipoxin A4 Receptor) with β-arrestin recruitment EC50 of 20 nM, calcium mobilization EC50 of 740 nM.

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Biological Activity

FPR2 agonist compound 8 is a potent, selective agonist of formyl peptide receptor 2 (FPR2/ALX, Lipoxin A4 Receptor) with β-arrestin recruitment EC50 of 20 nM, calcium mobilization EC50 of 740 nM.

Physicochemical Properties

M.Wt	417.31
Formula	C19H21BrN4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-(4-bromophenyl)ureido)-2-cyclopentyl-N-(pyridin-3-yl)acetamide

References

1. Maciuszek M, et al. Eur J Med Chem. 2021 Mar 15;214:113194.

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