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FPR2 inhibitor (S)-11l

Chemical Structure : FPR2 inhibitor (S)-11l

CAS No.: 2829263-20-7

FPR2 inhibitor (S)-11l (FPR2 agonist 2)

Catalog No.: PC-72355Not For Human Use, Lab Use Only.

FPR2 inhibitor (S)-11l is a potent, selective, brain penetrant FPR2 agonist with IC50 of 0.13 uM (hFPR2).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    FPR2 inhibitor (S)-11l is a potent, selective, brain penetrant FPR2 agonist with IC50 of 0.13 uM (hFPR2).

    Physicochemical Properties

    M.Wt 446.458
    Formula C25H20F2N4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-1-(3-(4-cyanophenyl)-1-(5-fluoroindolin-1-yl)-1-oxopropan-2-yl)-3-(4-fluorophenyl)urea

    References

    1. Margherita Mastromarino, et al. J Med Chem. 2022 Mar 24;65(6):5004-5028.

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