FTI-2148 | FTase inhibitor | Probechem Biochemicals

Chemical Structure : FTI-2148

Catalog No.: PC-22630Not For Human Use, Lab Use Only.

FTI-2148 is a potent, selective farnesyltransferase (FTase) inhibitor with IC50 of 1.4 nM, >1000-fold selective over GGTase I.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

FTI-2148 is a potent, selective farnesyltransferase (FTase) inhibitor with IC50 of 1.4 nM, >1000-fold selective over GGTase I.

M.Wt	452.57
Formula	C24H28N4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5-((((1H-imidazol-5-yl)methyl)amino)methyl)-2'-methyl-[1,1'-biphenyl]-2-carbonyl)-L-methionine

1. Sun J, et al. Cancer Res. 1999 Oct 1;59(19):4919-26.

2. Sun J, et al. Cancer Res. 2003 Dec 15;63(24):8922-9.

3. Carrico D, et al. Bioorg Med Chem. 2004 Dec 15;12(24):6517-26.