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Chemical Structure : FTI-2148
Catalog No.: PC-22630Not For Human Use, Lab Use Only.
FTI-2148 is a potent, selective farnesyltransferase (FTase) inhibitor with IC50 of 1.4 nM, >1000-fold selective over GGTase I.
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FTI-2148 is a potent, selective farnesyltransferase (FTase) inhibitor with IC50 of 1.4 nM, >1000-fold selective over GGTase I.
| M.Wt | 452.57 | |
| Formula | C24H28N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sun J, et al. Cancer Res. 1999 Oct 1;59(19):4919-26.
2. Sun J, et al. Cancer Res. 2003 Dec 15;63(24):8922-9.
3. Carrico D, et al. Bioorg Med Chem. 2004 Dec 15;12(24):6517-26.
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