Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Aromatase-Fadrozole
Fadrozole

Chemical Structure : Fadrozole

CAS No.: 102676-47-1

Fadrozole (CGS 16949A, FAD286, FAD 286)

Catalog No.: PC-60698Not For Human Use, Lab Use Only.

Fadrozole (CGS 16949A, FAD286) is a potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide.

Packing Price Stock Quantity
10 mg $88 In stock
25 mg $138 In stock
50 mg $218 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Fadrozole (CGS 16949A, FAD286) is a potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide.
Fadrozole lowers ovarian estrogen synthesis by gonadotropin-primed, androstenedione treated mice, suppresses hormone-dependent and -independent tumors in vivo.

Physicochemical Properties

M.Wt 223.279
Formula C14H13N3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile

References

1. Steele RE, et al. Steroids. 1987 Jul-Sep;50(1-3):147-61.

2. Schieweck K, et al. Cancer Res. 1988 Feb 15;48(4):834-8.

3. Juniewicz PE, et al. J Urol. 1988 Apr;139(4):827-31.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: