Chemical Structure : Fam20C inhibitor 3r
CAS No.: 2615358-19-3
Catalog No.: PC-49525Not For Human Use, Lab Use Only.
Fam20C inhibitor 3r is a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer.
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Fam20C inhibitor 3r is a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer.
Fam20C inhibitor 3r has strong anti-proliferative activity in MDA-MB-231 cells, with an IC50 = 5.986 μM.
Fam20C inhibitor 3r induces apoptosis and exerts obvious anti-migration activity in MDA-MB-231 cells.
Fam20C inhibitor 3r has good therapeutic potential in TNBC xenograft model without apparent toxicity.
M.Wt | 537.59 | |
Formula | C26H27N5O6S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-methoxy-N-(4-((4-((3,4,5-trimethoxyphenyl)amino)pyrimidin-2-yl)amino)phenyl)benzenesulfonamide |
1. Rongyan Zhao, et al. Eur J Med Chem. 2021 Jan 15;210:113088.
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