Famitinib (SHR1020) |CAS:1044040-56-3 Probechem Biochemicals

Chemical Structure : Famitinib

Famitinib (SHR1020, SHR-1020)

Catalog No.: PC-62597Not For Human Use, Lab Use Only.

Famitinib (SHR1020) is a structural analogue of sunitinib, novel and potent multi-targeted RTK inhibitor, including c-Kit, VEGFR2/3, PDGFRβ, FLT-1/3 receptor and c-RET.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Famitinib (SHR1020) is a structural analogue of sunitinib, novel and potent multi-targeted RTK inhibitor, including c-Kit, VEGFR2/3, PDGFRβ, FLT-1/3 receptor and c-RET.
Famitinib (SHR1020) demonstrates the higher potency in tumour growth inhibition in human tumour xenograft models compared with sunitinib.

Physicochemical Properties

M.Wt	410.493
Formula	C23H27FN4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-5-(2-(diethylamino)ethyl)-2-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-3-methyl-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one

References

1. Xie C, et al. Br J Pharmacol. 2013 Apr;168(7):1687-706.

2. Zhang W, et al. Chin Med J (Engl). 2013 Nov;126(22):4277-81.

3. Zhou A, et al. Cancer Chemother Pharmacol. 2013 Nov;72(5):1043-53.

4. Ge S, et al. Oncol Lett. 2016 Sep;12(3):1763-1768.

Famitinib (SHR1020, SHR-1020)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.