Chemical Structure : Fangchinoline
CAS No.: 436-77-1
Catalog No.: PC-27150Not For Human Use, Lab Use Only.
Fangchinoline is a natural bisbenzylisoquinoline alkaloid isolated from Stephania tetrandra whtinin extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis, inhibits HIV-1 replication by impairing gp160 proteolytic processing, suppresses FAK-mediated signaling pathway in cancer cells which highly expressed FAK, enhances antigen cross-presentation in a DNGR-1 (CLEC9A)-dependent manner.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $58 | In stock | |
| 50 mg | $88 | In stock | |
| 100 mg | $128 | In stock | |
| 250 mg | Get quote |
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Fangchinoline is a natural bisbenzylisoquinoline alkaloid isolated from Stephania tetrandra whtinin extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis, inhibits HIV-1 replication by impairing gp160 proteolytic processing, suppresses FAK-mediated signaling pathway in cancer cells which highly expressed FAK, enhances antigen cross-presentation in a DNGR-1 (CLEC9A)-dependent manner.
| M.Wt | 608.74 | |
| Formula | C37H40N2O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(11S,31S)-16,36,54-Trimethoxy-12,32-dimethyl-11,12,13,14,31,32,33,34-octahydro-2,6-dioxa-1(7,1),3(8,1)-diisoquinolina-5(1,3),7(1,4)-dibenzenacyclooctaphan-37-ol |
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1. Liao Y, et al. Adv Sci (Weinh). 2026 Jun 11:e76043.
2. Wan Z, et al. PLoS One. 2012;7(6):e39225.
3. Guo B, et al. J Drug Target. 2015 Apr;23(3):266-74.

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