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FerroLOXIN-1

Chemical Structure : FerroLOXIN-1

CAS No.: 2773428-48-9

FerroLOXIN-1

Catalog No.: PC-20923Not For Human Use, Lab Use Only.

FerroLOXIN-1 is a specific, small-molecule inhibitor of ferroptosis, inhibits 15LOX/PEBP1 catalytic complex rather than 15LOX alone, effectively suppresses ferroptosis in vitro and in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    FerroLOXIN-1 is a specific, small-molecule inhibitor of ferroptosis, inhibits 15LOX/PEBP1 catalytic complex rather than 15LOX alone, effectively suppresses ferroptosis in vitro and in vivo.

    Physicochemical Properties

    M.Wt 429.39
    Formula C23H16F5N3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(3-fluoro-4-(trifluoromethyl)benzyl)-1-(3-fluorophenyl)-4-phenyl-1H-imidazol-2-amine

    References

    1. Haider H Dar, et al. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2218896120.

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