Fidaxomicin (OPT-80, PAR-101) |CAS 873857-62-6 Probechem Biochemicals

Chemical Structure : Fidaxomicin

CAS No.: 873857-62-6

Fidaxomicin (OPT-80, PAR-101)

Catalog No.: PC-45367Not For Human Use, Lab Use Only.

Fidaxomicin (OPT-80, PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug and RNA polymerase inhibitor, shows potent anti-Clostridium difficile activity with MIC90 of 0.12 ug/mL.

Packing	Price	Stock
50 mg	$58	In stock
100 mg	$88	In stock
250 mg	$148	In stock
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Biological Activity

Fidaxomicin (OPT-80, PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug and RNA polymerase inhibitor, shows potent anti-Clostridium difficile activity with MIC90 of 0.12 ug/mL.
Fidaxomicin treatmen induced selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria.

Physicochemical Properties

M.Wt	1058.039
Formula	C52H74Cl2O18
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 33 mg/mL
Chemical Name/SMILES	Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1

References

1. Poxton IR, et al. Future Microbiol. 2010 Apr;5(4):539-48.
2. Ackermann G, et al. Antimicrob Agents Chemother. 2004 Jun;48(6):2280-2.