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Chemical Structure : Filaminast
CAS No.: 141184-34-1
Catalog No.: PC-63092Not For Human Use, Lab Use Only.
Filaminast (WAY-PDA-641, PDA-641, WAY-123641) is a potent and selective PDE4 inhibitor with IC50 of 420 nM, displays 36-fold selectivity over PDE3.
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Filaminast (WAY-PDA-641, PDA-641, WAY-123641) is a potent and selective PDE4 inhibitor with IC50 of 420 nM, displays 36-fold selectivity over PDE3.
Filaminast significantly potentiates the relaxant effects of albuterol, reverses tracheal contractions induced by prostaglandin F2 alpha, leukotriene D4 or histamine in a biphasic manner.
| M.Wt | 292.335 | |
| Formula | C15H20N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-(3-(Cyclopentyloxy)-4-methoxyphenyl)ethanone-(E)-O-(aminocarbonyl)oxime |
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1. Heaslip RJ, et al. J Pharmacol Exp Ther. 1994 Feb;268(2):888-96.
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