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Chemical Structure : Filastatin
CAS No.: 431996-53-1
Catalog No.: PC-70346Not For Human Use, Lab Use Only.
Filastatin is a small molecule inhibitor that inhibits adhesion of C. albicans to polystyrene.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $148 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | $398 | In stock | |
| 250 mg | Get quote |
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Filastatin is a small molecule inhibitor that inhibits adhesion of C. albicans to polystyrene.
Filastatin also inhibits binding of C. albicans to cultured human epithelial cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter, biofilm formation on silicone elastomers, and pathogenesis in a nematode infection model as well as alters fungal morphology in a mouse mucosal infection assay.
Filastatin is a chemical probe for study of multiple aspects of fungal pathogenesis.
| M.Wt | 359.81 | |
| Formula | C18H18ClN3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone |
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1. Fazly A, et al. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13594-9.
2. Vargas-Blanco D, et al. Ann Clin Microbiol Antimicrob. 2017 May 19;16(1):41.
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