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Chemical Structure : Filastatin
Catalog No.: PC-70346Not For Human Use, Lab Use Only.
A small molecule inhibitor that inhibits adhesion of C. albicans to polystyrene.
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A small molecule inhibitor that inhibits adhesion of C. albicans to polystyrene; also inhibits binding of C. albicans to cultured human epithelial cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter, biofilm formation on silicone elastomers, and pathogenesis in a nematode infection model as well as alters fungal morphology in a mouse mucosal infection assay; chemical probe for study of multiple aspects of fungal pathogenesis.
| M.Wt | 359.81 | |
| Formula | C18H18ClN3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Fazly A, et al. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13594-9.
2. Vargas-Blanco D, et al. Ann Clin Microbiol Antimicrob. 2017 May 19;16(1):41.
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