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Chemical Structure : Finafloxacin
CAS No.: 209342-40-5
Catalog No.: PC-43542Not For Human Use, Lab Use Only.
Finafloxacin is a fluoroquinolone antibiotic that demonstrates superior activity to ciprofloxacin under acidic conditions (pH5.8, A. baumannii isolates MIC=0.03-0.12ug/mL).
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Finafloxacin is a fluoroquinolone antibiotic that demonstrates superior activity to ciprofloxacin under acidic conditions (pH5.8, A. baumannii isolates MIC=0.03-0.12ug/mL).
Finafloxacin shows comparable activity to ciprofloxacin at pH 7.2.
Finafloxacin is a promising new antimicrobial agent for the treatment of A. baumannii infections at acidic body compartments.
| M.Wt | 398.3877 | |
| Formula | C20H19FN4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 6.4 mg/mL |
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| Chemical Name/SMILES |
3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo- |
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1. Higgins PG, et al. Antimicrob Agents Chemother. 2010 Apr;54(4):1613-5.
2. Emrich NC, J Antimicrob Chemother. 2010 Dec;65(12):2530-3.
3. Dalhoff A, et al. Antimicrob Agents Chemother. 2011 Apr;55(4):1814-8.
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