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Finafloxacin

Chemical Structure : Finafloxacin

CAS No.: 209342-40-5

Finafloxacin

Catalog No.: PC-43542Not For Human Use, Lab Use Only.

Finafloxacin is a fluoroquinolone antibiotic that demonstrates superior activity to ciprofloxacin under acidic conditions (pH5.8, A. baumannii isolates MIC=0.03-0.12ug/mL).

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Biological Activity

Finafloxacin is a fluoroquinolone antibiotic that demonstrates superior activity to ciprofloxacin under acidic conditions (pH5.8, A. baumannii isolates MIC=0.03-0.12ug/mL).
Finafloxacin shows comparable activity to ciprofloxacin at pH 7.2.
Finafloxacin is a promising new antimicrobial agent for the treatment of A. baumannii infections at acidic body compartments.

Physicochemical Properties

M.Wt 398.3877
Formula C20H19FN4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 6.4 mg/mL

Chemical Name/SMILES

3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-

References

1. Higgins PG, et al. Antimicrob Agents Chemother. 2010 Apr;54(4):1613-5.

2. Emrich NC, J Antimicrob Chemother. 2010 Dec;65(12):2530-3.

3. Dalhoff A, et al. Antimicrob Agents Chemother. 2011 Apr;55(4):1814-8.

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