Finazine |CAS:441745-52-4 Probechem Biochemicals

Chemical Structure : Finazine

Finazine

Catalog No.: PC-62223Not For Human Use, Lab Use Only.

Finazine is a high-affinity, brain penetrant sigma-1 and sigma 2 receptor ligand with Ki of 2.6 nM and 46 nM, respectively.

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Biological Activity

Finazine is a high-affinity, brain penetrant sigma-1 and sigma 2 receptor ligand with Ki of 2.6 nM and 46 nM, respectively。
Finazine potently binds to mammalian σ1 and altered threat-response behavior in mice.

Physicochemical Properties

M.Wt	363.505
Formula	C23H29N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-cinnamylpiperazin-1-yl)-N-(m-tolyl)propanamide

References

1. Rennekamp AJ, et al. Nat Chem Biol. 2016 Jul;12(7):552-8.

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Finazine

Biological Activity

Physicochemical Properties

References

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