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Chemical Structure : Fingolimod hydrochloride
CAS No.: 162359-56-0
Catalog No.: PC-42821Not For Human Use, Lab Use Only.
Fingolimod (FTY 720) hydrochloride is an immunomodulatory agent can be phosphorylated by SphK, then functions as a potent agonist of S1P receptors (S1P1/3/4/5) with EC50 of 0.3-5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $58 | In stock | |
| 250 mg | $88 | In stock | |
| 1 g | Get quote |
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Fingolimod (FTY 720) hydrochloride is an immunomodulatory agent can be phosphorylated by SphK, then functions as a potent agonist of S1P receptors (S1P1/3/4/5) with EC50 of 0.3-5 nM.
Fingolimod has no affitnity for S1P2.
Fingolimod alters lymphocyte trafficking and inhibits lymphocyte recirculation.
| M.Wt | 343.9318 | |
| Formula | C19H34ClNO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1,3-Propanediol, 2-amino-2-[2-(4-octylphenyl)ethyl]-, hydrochloride (1:1) |
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1. Mandala S, et al. Science. 2002 Apr 12;296(5566):346-9.
2. Suzuki S, et al. Transplantation. 1996 Jan 27;61(2):200-5.
3. Billich A, et al. J Biol Chem. 2003 Nov 28;278(48):47408-15.
4. Forrest M, et al. J Pharmacol Exp Ther. 2004 May;309(2):758-68.
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