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Chemical Structure : Firibastat
CAS No.: 648927-86-0
Catalog No.: PC-60511Not For Human Use, Lab Use Only.
Firibastat (QGC 001, RB 150) is a potent, orally active, centrally acting aminopeptidase inhibitor, the prodrug of the specific and selective aminopeptidase A inhibitor EC33.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $428 | In stock | |
| 100 mg | Get quote |
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Firibastat (QGC001, RB150) is a potent, orally active, centrally acting aminopeptidase inhibitor, the prodrug of the specific and selective aminopeptidase A inhibitor EC33.
Firibastat blocks the brain renin-angiotensin system activity and normalises blood pressure, with no effect on the systemic renin-angiotensin-aldosterone parameters and on PCop concentrations.
| M.Wt | 368.49 | |
| Formula | C8H20N2O6S4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-3-amino-4-(((S)-2-amino-4-sulfobutyl)disulfaneyl)butane-1-sulfonic acid |
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1. Balavoine F, et al. Clin Pharmacokinet. 2014 Apr;53(4):385-95.
2. Fournie-Zaluski MC, et al. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7775-80.
3. Bodineau L, et al. Hypertension. 2008 May;51(5):1318-25.
4. Marc Y, et al. J Hypertens. 2017 Sep 28. doi: 10.1097/HJH.0000000000001563.
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