Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Fleroxacin
CAS No.: 79660-72-3
Catalog No.: PC-49008Not For Human Use, Lab Use Only.
Fleroxacin (AM833, Ro23-6240) is a broad-spectrum fluoroquinolone antibiotic, with activity against a variety of Gram-positive and Gram-negative bacteria with MIC90 values of 0.05 to 3.13 ug/mL.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Fleroxacin (AM833, Ro23-6240) is a broad-spectrum fluoroquinolone antibiotic, with activity against a variety of Gram-positive and Gram-negative bacteria with MIC90 values of 0.05 to 3.13 ug/mL.
Fleroxacin (AM833, Ro23-6240) showed potent activity against members of the family Enterobacteriaceae, Neisseria spp., and Haemophilus influenzae and good activity against staphylococci, Pseudomonas aeruginosa, and Branhamella catarrhalis.
Fleroxacin (AM833, Ro23-6240) was as effective as ofloxacin and ciprofloxacin against systemic infections with Escherichia coli and Pseudomonas aeruginosa.
AM-833 exhibited good prophylactic activity against E. coli infections.
AM-833 also proved effective against localized infections such acute pneumonia and ascending urinary tract infections in mice.
| M.Wt | 369.344 | |
| Formula | C17H18F3N3O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid |
|
1. Chin NX, et al. Antimicrob Agents Chemother. 1986 Apr;29(4):675-80.
2. Hirai K, et al. Antimicrob Agents Chemother. 1986 Jun;29(6):1059-66.
3. Manek N, et al. Antimicrob Agents Chemother. 1986 Aug;30(2):330-2.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
