Florensocatib (HSK31858) | DPP-1 inhibitor

Chemical Structure : Florensocatib

Florensocatib (HSK31858, HSK-31858, CHF10196)

Catalog No.: PC-24134Not For Human Use, Lab Use Only.

Florensocatib (HSK31858, CHF10196) is a highly potent, reversible, and selective DPP1 (Cathepsin C, CatC) inhibitor, reversibly inhibitsrecombinant DPP-1 activity with an IC 50 of 3.7 nM.

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Biological Activity

Florensocatib (HSK31858, CHF10196) is a highly potent, reversible, and selective DPP1 (Cathepsin C, CatC) inhibitor, reversibly inhibitsrecombinant DPP-1 activity with an IC 50 of 3.7 nM.

Physicochemical Properties

M.Wt	438.46
Formula	C23H23FN4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)ethyl)-1,4-oxazepane-2-carboxamide

References

1. Wang Y, et al. Br J Clin Pharmacol. 2025 Aug;91(8):2262-2272.

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Florensocatib (HSK31858, HSK-31858, CHF10196)

Biological Activity

Physicochemical Properties

References

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