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Fluazinam

Chemical Structure : Fluazinam

CAS No.: 79622-59-6

Fluazinam

Catalog No.: PC-27213Not For Human Use, Lab Use Only.

Fluazinam is a broad-spectrum, orally active fungicide and acaricide and potent uncoupler of oxidative phosphorylation.

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Biological Activity

Fluazinam is a broad-spectrum, orally active fungicide and acaricide and potent uncoupler of oxidative phosphorylation.
Fluazinam targets mitochondrial complex I to induce reactive oxygen species-dependent cytotoxicity in SH-SY5Y cells.
Fluazinam binds with the ATP synthase subunit FfATPh but not with FfATP5 or FfATPb of Fusarium fujikuroi.

Physicochemical Properties

M.Wt 465.09
Formula C13H4Cl2F6N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Chloro-N-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)pyridin-2-amine

References

1. Tokutake N, et al. iochim Biophys Acta. 1991 May 6;1057(3):377-83.

2. Mitani S, et al. Pest Manag Sci. 2003 Mar;59(3):287-93.

3. Lee JE, et al. Neurotoxicology. 2011 Dec;32(6):702-10.

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