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Flupirtine

Chemical Structure : Flupirtine

CAS No.: 56995-20-1

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Flupirtine (D-9998)

Catalog No.: PC-45127Not For Human Use, Lab Use Only.

A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Flupirtine (D-9998) is a selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties.
Flupirtine is a centrally acting non-opioid analgesic used as an analgesic for acute and chronic pain.

Physicochemical Properties

M.Wt 304.3195
Formula C15H17FN4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Carbamic acid, N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-, ethyl ester

References

1. Szelenyi I, et al. Inflamm Res. 2013 Mar;62(3):251-8.

2. Harish S, et al. J Anaesthesiol Clin Pharmacol. 2012 Apr;28(2):172-7.

3. Hedegaard ER, et al. J Pharmacol Exp Ther. 2016 Apr;357(1):94-102.

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