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Fluvastatin

Chemical Structure : Fluvastatin

CAS No.: 93957-54-1

Fluvastatin (XU 62-320)

Catalog No.: PC-27085Not For Human Use, Lab Use Only.

Fluvastatin (XU 62-320) is a potent, selective and, competitive HMG-CoA reductase (HMGCR) inhibitor with IC50 of 8 nM, also specifically targets the interaction between KRT18 and LDHA, thereby inhibiting meningioma proliferation by suppressing glycolysis and PI3K/AKT signaling.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Fluvastatin (XU 62-320) is a potent, selective and, competitive HMG-CoA reductase (HMGCR) inhibitor with IC50 of 8 nM, also specifically targets the interaction between KRT18 and LDHA, thereby inhibiting meningioma proliferation by suppressing glycolysis and PI3K/AKT signaling.

Physicochemical Properties

M.Wt 411.47
Formula C24H26FNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

rel-(3R,5S,E)-7-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid

References

1. Makabe S, et al. Atherosclerosis. 2010 Dec;213(2):377-84.

2. Li H, et al. Cancer Lett. 2026 Jun 15:218680.

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