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Fmoc-Val-Cit-PAB-PNP

Chemical Structure : Fmoc-Val-Cit-PAB-PNP

CAS No.: 863971-53-3

Fmoc-Val-Cit-PAB-PNP

Catalog No.: PC-45818Not For Human Use, Lab Use Only.

A cathepsin B-cleavable dipeptide linker for antibody-drug-conjugation (ADC).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A cathepsin B-cleavable dipeptide linker for antibody-drug-conjugation (ADC).

Physicochemical Properties

M.Wt 766.7957
Formula C40H42N6O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 40 mg/mL

Chemical Name/SMILES

L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-

References

1. Dubowchik GM, et al. Bioconjug Chem. 2002 Jul-Aug;13(4):855-69.

2. Doronina SO, et al. Bioconjug Chem. 2008 Oct;19(10):1960-3.

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