Forazemin | Peptide deformylase inhibitor

Chemical Structure : Forazemin

Forazemin (BB-83698)

Catalog No.: PC-26790Not For Human Use, Lab Use Only.

Forazemin (BB-83698) is a potent, orally active peptide deformylase (PDF) inhibitor, shows antibacterial potency for gram-positive pathogens with MIC50 of 0.25 ug/mL and 0.06 ug/mL for Streptococcus pneumoniae and Moraxella catarrhalis.

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Biological Activity

Physicochemical Properties

M.Wt	530.67
Formula	C28H42N4O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-((S)-1-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3-cyclopentyl-2-((N-hydroxyformamido)methyl)propanamide

References

1. Lofland D, et al. J Antimicrob Chemother. 2004 Apr;53(4):664-8.

2. Wise R, et al. Antimicrob Agents Chemother. 2002 Apr;46(4):1117-8.

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Forazemin (BB-83698)

Biological Activity

Physicochemical Properties

References

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