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Forsythiaside A

Chemical Structure : Forsythiaside A

CAS No.: 79916-77-1

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Forsythiaside A

Catalog No.: PC-27875Not For Human Use, Lab Use Only.

Forsythiaside A is an orally active phenylethanoid glycoside isolated from the dried fruits of Forsythia suspensa within anti-inflammatory, anti-oxidant, and antioxidant activities, inhibits NF-κB activation and up-regulates the expression of Nrf2 and heme oxygenase-1 (HO-1).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Forsythiaside A is an orally active phenylethanoid glycoside isolated from the dried fruits of Forsythia suspensa within anti-inflammatory, anti-oxidant, and antioxidant activities, inhibits NF-κB activation and up-regulates the expression of Nrf2 and heme oxygenase-1 (HO-1).

Physicochemical Properties

M.Wt 624.59
Formula C29H36O15
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-(2R,3S,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-4,5-dihydroxy-2-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3-yl 3-(3,4-dihydroxyphenyl)acrylate

References

1. Kim JM, et al. Eur J Pharmacol. 2011 Jun 25;660(2-3):326-33.

2. Nazemiyeh H, et al. J Nat Med. 2008 Jan;62(1):91-5.

3. Cheng G, et al. Exp Ther Med. 2014 Jan;7(1):179-184.

4. Pan CW, et al. Int Immunopharmacol. 2015 May;26(1):80-5.

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