Fosaprepitant dimeglumine

Chemical Structure : Fosaprepitant dimeglumine

CAS No.: 265121-04-8

Catalog No.: PC-25517Not For Human Use, Lab Use Only.

Fosaprepitant dimeglumine (MK-0517) is a prodrug of Aprepitant (PC-42185), which is a potent, selective neurokinin-1 receptor (NK1R)antagonist

Packing	Price	Stock
25 mg	$98	In stock
50 mg	$148	In stock
100 mg	$238	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Fosaprepitant dimeglumine (MK-0517) is a prodrug of Aprepitant (PC-42185), which is a potent, selective neurokinin-1 receptor (NK1R)antagonist

M.Wt	1004.84
Formula	C37H56F7N6O16P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol ((3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)(2:1)

1. Bayati S, et al. Eur J Pharmacol. 2016 Nov 15;791:274-283.

2. Pranav Prasoon, et al. Indian J Pharmacol. 2016 Jul-Aug; 48(4): 394-398.

3. Navari RM. Expert Opin Investig Drugs. 2007 Dec;16(12):1977-85.