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Chemical Structure : Foxy-5
CAS No.: 881188-51-8
Catalog No.: PC-61759Not For Human Use, Lab Use Only.
Foxy-5 (formyl-Met-Asp-Gly-Cys-Glu-Leu) is a Wnt5A mimicking hexapeptide that inhibits breast cancer metastasis in vivo by targeting cell motility.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Foxy-5 (formyl-Met-Asp-Gly-Cys-Glu-Leu) is a Wnt5A mimicking hexapeptide that inhibits breast cancer metastasis in vivo by targeting cell motility.
Foxy-5 also significantly inhibits the initial metastatic dissemination of prostate cancer cells to regional and distal lymph nodes.
Foxy-5 specifically targets invasion without affecting apoptosis or viability of WNT5A-low prostate cancer cells.
| M.Wt | 694.77 | |
| Formula | C26H42N6O12S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2S,5S,8R,14S)-5-(2-carboxyethyl)-14-((S)-2-formamido-4-(methylthio)butanamido)-2-isobutyl-8-(mercaptomethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecanedioic acid |
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1. Säfholm A, et al. Clin Cancer Res. 2008 Oct 15;14(20):6556-63.
2. Ford CE, et al. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3919-24.
3. Canesin G, et al. PLoS One. 2017 Sep 8;12(9):e0184418.
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