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Framycetin

Chemical Structure : Framycetin

CAS No.: 119-04-0

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Framycetin (Fradiomycin B;Neomycin B)

Catalog No.: PC-45392Not For Human Use, Lab Use Only.

An aminoglycoside antibiotic.

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10 mg $56 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

An aminoglycoside antibiotic; selectively inhibits production of the mature miRNA, boosts a downstream protein, and inhibits invasion in HCC cell lines; a second-line agent for hepatic encephalopathy (HE) and bacterial infections due to cirrhosis.

Bacterial Infection

Approved

Physicochemical Properties

M.Wt 614.6437
Formula C23H46N6O13
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 60 mg/mL

Chemical Name/SMILES

D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-

References

1. Brinson RG, et al. Biochemistry. 2009 Jul 28;48(29):6988-97.

2. Childs-Disney JL, et al. ACS Chem Biol. 2016 Feb 19;11(2):375-80.

3. Bera S, et al. Molecules. 2012 Aug 2;17(8):9129-41.

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