Frespaciguat | sGC stimulator | Probechem Biochemicals

Chemical Structure : Frespaciguat

Catalog No.: PC-24955Not For Human Use, Lab Use Only.

Frespaciguat (MK-5475) is a highly potent, small molecule soluble guanylate cyclase (sGC) stimulator.

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Biological Activity

Frespaciguat (MK-5475) is a highly potent, small molecule soluble guanylate cyclase (sGC) stimulator.

M.Wt	608.95
Formula	C27H22ClF5N6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-(4-(4-amino-2-(6-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazol-3-yl)-5-methyl-6-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl)propanoic acid

1. Bajwa EK, et al. Respir Med. 2023 Jan;206:107065.