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Chemical Structure : Fumagillin
CAS No.: 23110-15-8
Catalog No.: PC-22787Not For Human Use, Lab Use Only.
Fumagillin (NSC9168) is an antimicrobial compound that covalently binds and inhibits the methionine aminopeptidase MetAP-2, inhibits angiogenesis and cancer cell proliferation.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $178 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Fumagillin (NSC9168) is an antimicrobial compound that covalently binds and inhibits the methionine aminopeptidase MetAP-2, inhibits angiogenesis and cancer cell proliferation.
Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
| M.Wt | 458.55 | |
| Formula | C26H34O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2E,4E,6E,8E)-10-(((3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl)oxy)-10-oxodeca-2,4,6,8-tetraenoic acid |
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1. Sin N, et al. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6099-103.
2. Griffith EC, et al. Chem Biol. 1997 Jun;4(6):461-71.
3. Griffith EC, et al. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15183-8.
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