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Chemical Structure : Fumarase-IN-2 sodium
Catalog No.: PC-42019Not For Human Use, Lab Use Only.
Fumarase-IN-2 sodium is a cell-permeable small molecule inhibitor of Fumarase (fumarate hydratase), an enzyme of the tricarboxylic acid cycle (TCA cycle).
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Fumarase-IN-2 sodium is a cell-permeable small molecule inhibitor of Fumarase (fumarate hydratase), an enzyme of the tricarboxylic acid cycle (TCA cycle).
Fumarase-IN-2 sodium elicits a nutrient-dependent cytotoxicity in a number of cancer cell lines.
Fumarase-IN-2 sodium displays increased growth-inhibitory activity toward SW620 cell line grown in the absence of glucose (mean IC50=2.2 uM).
| M.Wt | 440.4668 | |
| Formula | C25H25N2NaO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 10.66 mg/mL |
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1. Takeuchi T, et al. J Am Chem Soc. 2015 Jan 21;137(2):564-7.
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