Funapide (XEN402) | NaV1.7/Nav1.8 inhibitor

Chemical Structure : Funapide

CAS No.: 1259933-16-8

Catalog No.: PC-61869Not For Human Use, Lab Use Only.

Funapide (XEN402, TV-45070) is a potent and selective, orally available sodium channel Nav1.7 and Nav1.8 blocker for treatment of pain.

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Biological Activity

Funapide (XEN402, TV-45070) is a potent and selective, orally available sodium channel Nav1.7 and Nav1.8 blocker for treatment of pain.

M.Wt	429.35
Formula	C22H14F3NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3'S)-1'-{[5-(trifluoromethyl)furan-2-yl]methyl}-2H,6H-spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

1. Bagal SK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.

2. Goldberg YP, et al. Pain. 2012 Jan;153(1):80-5.