Chemical Structure : Furmonertinib mesylate
CAS No.: 2130958-55-1
Catalog No.: PC-35641Not For Human Use, Lab Use Only.
Furmonertinib mesylate (AST-2818, Alflutinib mesylate) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.
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Furmonertinib mesylate (AST-2818, Alflutinib mesylate) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.
M.Wt | 664.705 | |
Formula | C29H35F3N8O5S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate |
1. PCT Int. Appl. (2017), WO 2017152707 A1 20170914.
2. PCT Int. Appl. (2017), WO 2017152706 A1 20170914.
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