G-9791 |CAS:1926204-95-6 Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Cell Cycle/DNA Damage-p21-activated Kinase (PAK)-G-9791

Chemical Structure : G-9791

G-9791 (G 9791;G9791)

Catalog No.: PC-60221Not For Human Use, Lab Use Only.

G-9791 (G9791) is a potent and selective group I PAK (pan-PAK1/2/3) inhibitor with Ki of 0.95/2 nM for PAK1/2, respectively.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

G-9791 (G9791) is a potent and selective group I PAK (pan-PAK1/2/3) inhibitor with Ki of 0.95/2 nM for PAK1/2, respectively.
G-9791 displays 57-fold selectivity over Lck kinase.
G-9791 inhibits the phosphorylation of residue S298 of MEK1 in EBC1 cells with IC50 of 33 nM.

Physicochemical Properties

M.Wt	508.98
Formula	C26H26ClFN6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(2-Chloro-4-(3-methyl-2-oxopyridin-1(2H)-yl)phenyl)-8-(2-(3-fluoro-1-methylazetidin-3-yl)ethyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one

References

1. Rudolph J, et al. J Med Chem. 2016 Jun 9;59(11):5520-41.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

G-9791 (G 9791;G9791)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.