Catalog No.: PC-61050Not For Human Use, Lab Use Only.
GATA4-IN-3 is a novel small molecule that inhibits GATA4/NKX2-5 transcriptional synergy with IC50 of 3 uM, with no activity on the protein kinases involved in the regulation of GATA4 phosphorylation.
GATA4-IN-3 is a novel small molecule that inhibits GATA4/NKX2-5 transcriptional synergy with IC50 of 3 uM, with no activity on the protein kinases involved in the regulation of GATA4 phosphorylation.
GATA4-IN-3 also inhibits the ET-1-stimulated BNP gene expression.
GATA4-IN-3 inhibits hypertrophic growth in a cardiomyocyte hypertrophy model, without effect on apoptotic cell death.
