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GATA4 activator 7

Chemical Structure : GATA4 activator 7

CAS No.: 878090-53-0

GATA4 activator 7

Catalog No.: PC-61051Not For Human Use, Lab Use Only.

GATA4 activator 7 is a novel small molecule that activates GATA4/NKX2-5 transcriptional synergy with EC50 of 7 uM in cell reporter assay.

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    Biological Activity

    GATA4 activator 7 is a novel small molecule that activates GATA4/NKX2-5 transcriptional synergy with EC50 of 7 uM in cell reporter assay.

    Physicochemical Properties

    M.Wt 411.904
    Formula C21H18ClN3O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(4-chlorophenyl)-5-methyl-N-(4-methyl-4,5-dihydrothiazol-2-yl)-3-phenylisoxazole-4-carboxamide

    References

    1. Välimäki MJ, et al. J Med Chem. 2017 Sep 28;60(18):7781-7798.

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