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Chemical Structure : GB111-NH2
CAS No.: 956479-18-8
Catalog No.: PC-61355Not For Human Use, Lab Use Only.
GB111-NH2 (Z-Phe-Lys-AOMK) is a novel cysteine cathepsin inhibitor that blocks the activity of cathepsins B, L and S.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $458 | In stock | |
| 10 mg | $688 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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GB111-NH2 (Z-Phe-Lys-AOMK) is a novel cysteine cathepsin inhibitor that blocks the activity of cathepsins B, L and S.
GB111-NH2 (Z-Phe-Lys-AOMK) inhibits autophagy and increases oxidative stress, specifically trigger macrophage cell death.
| M.Wt | 573.68 | |
| Formula | C33H39N3O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-7-amino-3-((S)-2-(((benzyloxy)carbonyl)amino)-3-phenylpropanamido)-2-oxoheptyl 2,6-dimethylbenzoate |
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1. Salpeter SJ, et al. Oncogene. 2015 Dec 10;34(50):6066-78.
2. Blum G, et al. Nat Chem Biol. 2005 Sep;1(4):203-9.
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