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GBR 12935

Chemical Structure : GBR 12935

CAS No.: 76778-22-8

GBR 12935 (GBR12935;GBR-12935)

Catalog No.: PC-42929Not For Human Use, Lab Use Only.

A potent and selective dopamine reuptake inhibitor with IC50 of 3.7 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent and selective dopamine reuptake inhibitor with IC50 of 3.7 nM; shows 78-fold selectivity versus 5-HT reuptake.

Physicochemical Properties

M.Wt 414.5824
Formula C28H34N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Piperazine, 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-

References

1. Matecka D, et al. J Med Chem. 1996 Nov 22;39(24):4704-16.

2. Bhargava HN, et al. Pharmacology. 1996 Apr;52(4):243-51.

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