GDC-0834 | BTK inhibitor | Probechem Biochemicals

Chemical Structure : GDC-0834

CAS No.: 1133432-49-1

Catalog No.: PC-26464Not For Human Use, Lab Use Only.

GDC-0834 is a potent, selective BTK inhibitor with IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively.

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10 mg	$398	In stock
25 mg	$598	In stock
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Biological Activity

GDC-0834 is a potent, selective BTK inhibitor with IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively.

M.Wt	596.75
Formula	C33H36N6O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(3-(6-((4-(1,4-Dimethyl-3-oxopiperazin-2-yl)phenyl)amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl)-2-methylphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamide

1. Liu L, et al. J Pharmacol Exp Ther. 2011 Jul;338(1):154-63.

2. Young WB, et al. Bioorg Med Chem Lett. 2015 Mar 15;25(6):1333-7.