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Chemical Structure : GDU-952
Catalog No.: PC-21481Not For Human Use, Lab Use Only.
GDU-952 is a novel small molecule aryl hydrocarbon receptor (AhR) agonist, activates and induces nuclear translocation of AhR.
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GDU-952 is a novel small molecule aryl hydrocarbon receptor (AhR) agonist, activates and induces nuclear translocation of AhR.
GDU-952 (1 uM) treatment obviously increased CYP1A1 generation, induces nuclear translocation of AhR in RAW264.7 macrophages.
GDU-952 decreases IgE serum levels, to inhibit pro-inflammatory cytokines such as IL-6 and TNF-α and to induce immunoregulatory effects through restoring Th1/Th2 immune balance and promoting CD4+FOXP3+regulatory T (Treg) populations in AD skin lesions.
| M.Wt | 284.37 | |
| Formula | C17H16O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Liang YH, et al. Biochem Pharmacol. 2023 Nov;217:115835.
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