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GH8HA01

Chemical Structure : GH8HA01

CAS No.:

GH8HA01

Catalog No.: PC-49539Not For Human Use, Lab Use Only.

GH8HA01 is a highly potent, selective HDAC8 inhibitor with Ki of 0.67 nM, highly selective against HDAC8 compared to other HDACs.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GH8HA01 is a highly potent, selective HDAC8 inhibitor with Ki of 0.67 nM, highly selective against HDAC8 compared to other HDACs.

Physicochemical Properties

M.Wt 1091.189
Formula C55H66N10O14
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3S,6S,9S,12S,15S,18S,21S)-9-((1H-indol-3-yl)methyl)-21-amino-12,15-dibenzyl-3-carbamoyl-6-(2-carboxyethyl)-18-(6-(hydroxyamino)-6-oxohexyl)-22-(4-hydroxyphenyl)-5,8,11,14,17,20-hexaoxo-4,7,10,13,16,19-hexaazadocosanoic acid

References

1. Jared S Morse, et al. Protein Sci. 2022 Nov 16;e4512.

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