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GH8HA01

Chemical Structure : GH8HA01

CAS No.:

GH8HA01

Catalog No.: PC-49539Not For Human Use, Lab Use Only.

GH8HA01 is a highly potent, selective HDAC8 inhibitor with Ki of 0.67 nM, highly selective against HDAC8 compared to other HDACs.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GH8HA01 is a highly potent, selective HDAC8 inhibitor with Ki of 0.67 nM, highly selective against HDAC8 compared to other HDACs.

    Physicochemical Properties

    M.Wt 1091.189
    Formula C55H66N10O14
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (3S,6S,9S,12S,15S,18S,21S)-9-((1H-indol-3-yl)methyl)-21-amino-12,15-dibenzyl-3-carbamoyl-6-(2-carboxyethyl)-18-(6-(hydroxyamino)-6-oxohexyl)-22-(4-hydroxyphenyl)-5,8,11,14,17,20-hexaoxo-4,7,10,13,16,19-hexaazadocosanoic acid

    References

    1. Jared S Morse, et al. Protein Sci. 2022 Nov 16;e4512.

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