GJ103 sodium salt |CAS:1459687-96-7 Probechem Biochemicals

Chemical Structure : GJ103 sodium salt

CAS No.: 1459687-96-7

GJ103 sodium salt (GJ 103 sodium salt;GJ-103 sodium salt)

Catalog No.: PC-42333Not For Human Use, Lab Use Only.

A novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene.

Packing	Price	Stock
5 mg	$264	In stock
10 mg	$400	In stock
50 mg	$1200	In stock
100 mg	$1680	In stock

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Biological Activity

A novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene; induces ATM kinase on both TGA and TAG stop codons and restores ATMpSer1981 autophosphorylation and SMC1pSer966 transphosphorylation in A-T cells.

Physicochemical Properties

M.Wt	364.35418928
Formula	C16H13N4NaO3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 34 mg/mL
Chemical Name/SMILES	Acetic acid, 2-[[4-(3-methoxyphenyl)-5-(2-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-, sodium salt (1:1)

References

1. Du L, et al. Mol Ther. 2013 Sep;21(9):1653-60.

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GJ103 sodium salt (GJ 103 sodium salt;GJ-103 sodium salt)

Biological Activity

Physicochemical Properties

References

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