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Chemical Structure : GJ103 sodium salt
CAS No.: 1459687-96-7
Catalog No.: PC-42333Not For Human Use, Lab Use Only.
A novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $264 | In stock | |
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock |
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A novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene; induces ATM kinase on both TGA and TAG stop codons and restores ATMpSer1981 autophosphorylation and SMC1pSer966 transphosphorylation in A-T cells.
| M.Wt | 364.35418928 | |
| Formula | C16H13N4NaO3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 34 mg/mL |
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| Chemical Name/SMILES |
Acetic acid, 2-[[4-(3-methoxyphenyl)-5-(2-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-, sodium salt (1:1) |
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1. Du L, et al. Mol Ther. 2013 Sep;21(9):1653-60.
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