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Chemical Structure : GK563
Catalog No.: PC-36137Not For Human Use, Lab Use Only.
GK563 (GK-563) is a potent, selective inhibitor of Ca2+-independent phospholipase A2 (GVIA iPLA2) with IC50 of 1 nM, >20,000-fold selectivity over GIVA cPLA2.
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GK563 (GK-563) is a potent, selective inhibitor of Ca2+-independent phospholipase A2 (GVIA iPLA2) with IC50 of 1 nM, >20,000-fold selectivity over GIVA cPLA2.
GK563 reduce β-cell apoptosis induced by proinflammatory cytokines.
| M.Wt | 246.35 | |
| Formula | C16H22O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dedaki C, et al. J Med Chem. 2019 Mar 12. doi: 10.1021/acs.jmedchem.8b01216.
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