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Chemical Structure : GL-1196
Catalog No.: PC-62721Not For Human Use, Lab Use Only.
GL-1196 is a PAK4 inhibitor that effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclinD1 pathway and CDK4/6 expression.
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GL-1196 is a PAK4 inhibitor that effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclinD1 pathway and CDK4/6 expression.
GL-1196 prominently inhibits the invasion of human gastric cancer cells in parallel with blockage of the PAK4/LIMK1/cofilin pathway.
GL-1196 also inhibits the formation of filopodia and induced cell elongation in SGC7901 and BGC823 cells.
| M.Wt | 398.861 | |
| Formula | C20H15ClN2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zhang J, et al. Int J Mol Sci. 2016 Apr 11;17(4):470.
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