Chemical Structure : GLP-26
CAS No.: 2133017-36-2
Catalog No.: PC-35254Not For Human Use, Lab Use Only.
GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM.
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|---|---|---|---|
| 5 mg | $148 | In stock | |
| 10 mg | $218 | In stock | |
| 25 mg | $378 | In stock | |
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GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM.
GLP26 is a potent inhibitor of cccDNA formation and HBeAg production against the mutant core T109I, demonstrates synergistic activity with ETV in the HepAD38 system, reducing HBV DNA replication.
| M.Wt | 373.36 | |
| Formula | C19H17F2N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(3,4-difluorophenyl)-1,3,5-trimethyl-4-(2-oxo-2-(prop-2-yn-1-ylamino)acetyl)-1H-pyrrole-2-carboxamide |
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1. Nijampatnam B, et al. Curr Opin Chem Biol. 2019 Jun;50:73-79.

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